Webinar | Optimising schistosomiasis treatment for preschool-aged children: A pragmatic approach from research to practice

08 Dec 2025

This webinar shared findings from an important clinical trial in Uganda which evaluated the safety and efficacy of praziquantel at 40 mg/kg versus 80 mg/kg in preschool-aged children with intestinal schistosomiasis. The study found both doses were safe, with higher efficacy observed at 80 mg/kg, providing critical evidence to guide treatment strategies for young children in endemic regions. The webinar discussed these findings and how they can contribute to a practical approach to include preschool-aged children in schistosomiasis control and elimination efforts.

Speakers: 

  • ​Prof Amaya Bustinduy (London School of Hygiene & Tropical Medicine (LSHTM), UK)
  • Dr Andrew Edielu (London School of Hygiene & Tropical Medicine (LSHTM), UK; MRC Uganda Virus Research Institute (MRC/UVRI), Uganda; LSHTM Uganda Research Unit)
  • Dr Narcis B Kabatereine (Consultant and advisory to Ministry of Health, Uganda)
  • With remarks from Dr Amadou Garba (WHO)​​

Listen to the talks in French

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Preschool schistosomiasis: an introduction

Prof Amaya Bustinduy (London School of Hygiene & Tropical Medicine (LSHTM), UK)

Optimising schistosomiasis treatments: the Praziquantel in Preschool-aged Children (PIP) trial 

Dr Andrew Edielu (London School of Hygiene & Tropical Medicine (LSHTM), UK; MRC Uganda Virus Research Institute (MRC/UVRI), Uganda; LSHTM Uganda Research Unit)

Treating schistosomiasis in children, paediatric formulation & crushed praziquantel tablets (Uganda)

Dr Narcis B Kabatereine (Consultant and advisory to Ministry of Health, Uganda)

WHO perspectives on treatment of schistosomiasis in preschool age children

Remarks from Dr Amadou Garba (WHO)​​

Research Webinar